2009 |
2008 |
2007 |
2006 |
2005 |
2004 |
2003 |
2001 |
2010
- MUT/2010/01 Review of COM Guidance: Draft discussion paper: Overview of Strategy for Testing of Chemicals for Genotoxicity
Appendix 1 - Guidance statements
Appendix 2 - Guidance on a strategy for testing of chemicals for genotoxicity
- MUT/2010/02 Draft Discussion Paper:Guidance Statement on Thresholds for in vivo mutagens:(4th draft)
- MUT/2010/03 GADD45a-GFP 'GreenScreenHC' Genotoxicity Assay Follow Up (in closed session).
- MUT/2010/04 GADD45a-GFP 'GreenScreenHC' Genotoxicity Assay: Further Analysis (in closed session).
- MUT/2010/05 GADD45a-GFP 'GreenScreenHC' Genotoxicity Assay: Further Analyses of the High-throughput Assay. (in closed session).
- MUT/2010/06 Review of Government Funded research: paper on Organophosphates and DNA Damage
- MUT/2010/07 Draft Annual Report for 2009.
2009___
- MUT/09/02 Thresholds for in-vivo mutagens and genotoxic carcinogens - draft discussion paper.
- MUT/09/03 Toxicogenomics: Further update discussion paper.
- MUT/09/04 Annual Report 2008
- MUT/09/05 Draft discussion paper: Genotoxicity of Tobacco Products
- MUT/09/06 Draft COT Scoping paper on Toxicology of Tobacco Products (TOX/2008/01)
- MUT/09/07 Regulatory Aspects surrounding the toxicological testing of Tobacco Products
- MUT/09/08 Thresholds for in-vivo genotoxins
- MUT/09/09 Draft Guidance document: Risk Assessment of in-vivo mutagens
- MUT/09/10 Mouse Lymphoma Assay
- MUT/09/11 Horizon Scanning Paper 2009
- MUT/09/12 Draft discussion paper: Guidance Series: Risk Assessment of in-vivo mutagens
- MUT/09/13 Draft Discussion Paper: Genotoxicity of Parachloroaniline
- annex 1 Referral letter from ACP
- MUT/09/13 Addendum annexe header 1 & annexe header 2
- MUT/09/14 GADD 45a Assay
- MUT/08/1 - Review of Genotoxicity of Acrylamide: Review of additional data December 2007 and January 2008 from PPG
- MUT/08/3 - Review of COM guidance: Discussion paper on scope and process
- MUT/08/4 - Draft working paper on mutagenicity assessment of chemical mixtures
- MUT/08/6 - Additional data on acrylamide
- MUT/08/7 - Overview of genotoxicity of glycidamide
- MUT/08/8 - Review of genotoxicity data on phenol
- MUT/08/9 - Generic papers on hypothermia and hyperthermia and induction of MN in rodent
- MUT/08/10 - Mutagenicity evaluation of impurities
- MUT/08/11 - Scope of review of COM guidance
- MUT/08/12 - Consideration of draft ICH guidance
- MUT/08/13 - Aclonifen (closed session)
- MUT/08/14 - annex 1, annex 2, Attachments - Toxicogenomics: Update discussion paper
- MUT/08/15 - addendum 1 - Second Draft Working Paper on the Genotoxicity of Acrylamide
- MUT/08/16 - Phenol: Consideration of Draft Working Paper
- MUT/08/17 - Horizon Scan (2008)
- MUT/08/18 - Review of COM Guidance: Secretariat Meeting
- MUT/08/19 - Provisional informatin in ILSI-HESI research on Toxicogenomic
approaches to genotoxicity
- MUT/08/20 - Fourth Draft Statement on the Genotoxicity of Acrylamide
2007
- MUT/07/01 - Formaldehyde: Evidence for systemic mutagenicity
- MUT/07/02 - The Lowest Effective Dose (LED for in-vivo genotoxicity); a possible approach to mutagen potency ranking
- MUT/07/03 - Initial discussion paper on mutagenicity of mixtures
- MUT/07/04 - Benzimidazoles: an approach to defining a common aneugenic grouping
- MUT/07/05 - Paper for information only
- MUT/07/06 - Strategies for mutagenicity testing post 7th Amendment to the EU Cosmetics Directive. Discussion of commentary paper from Tweats DJ et al published Mutagenesis, 2 Dec 2006
- MUT/07/07 - Draft Annual report for 2006
- MUT/07/8 - Use of the LED for potency ranking of in-vivo mutagens
- MUT/07/9 - Mutagenicity of Terephthalic acid - Additional cytogenetics data
- MUT/07/10 - Additional summary information on GADD45a-GFP assay
- MUT/07/11 - Development of an OECD guideline for the in-vitro Micronucleus assay
- MUT/07/12 - Draft working paper on Formaldehyde (written comments)
- MUT/07/14 Presentation - The TK6 GADD45a-GFP Genotoxicity assay Dr R Walmsley (University of Manchester)
- MUT/07/15 - Mutagenicity of mixtures. 2nd discussion paper. Evaluation of interactions using mutagenicity tests
- MUT/07/18 - Toxicogenomics: Update on 2004
- MUT/07/19 - Horizon scanning
- MUT/07/20 - Aneuploidy: Action both oncogenically and as a tumour suppressor
- MUT/07/22 - Revised code of practice for observers
- MUT/07/23 - Sodium Benzoate and Potassium Sorbater
- MUT/07/24 - Draft statement on Terephthalic Acid
2006
- MUT/06/1 ; Annex 1 ; Annex 2 -- Background Background variation in Micronuclei in peripheral blood lymphocytes; Discussion paper on risk factors
- MUT/06/2 - Biological Effects of Wear Debris Generated from Metal on Metal Bearing Surfaces: Evidence for Genotoxicity
- MUT/06/3 - A comparison of the sensitivities of the in vivo rat liver UDS assay with the in vivo COMET assay
- MUT/06/8 - Benzimidazoles: Discussion of a common mechanism group (Annex 1 in confidence)
- MUT/06/9 - Terephthalic acid: Update on mutagenicity data (Annexes A - E in confidence)
- MUT/06/10 - Comparative risk assessment: Initial discussions
- MUT/06/11 - Discussion of risk factors for background variance of cytogenticity in Peripheral Blood Lymphocytes
- MUT/06/14 - Benzimidazoles - Conclusions
- MUT/06/15 - Role of methylation status: Transgenerational effects of methylation
- MUT/06/16 - Comparative risk assessment update of COC discussion
- MUT/06/17 - Do dose response thresholds exist for genotoxic alkylating agents? GJS Jenkins et al Mutagenesis, 20, (6), 389-398, 2005. Evidence for practical thresholds for clastogenic agents.
- MUT/06/19 - Horizon scanning 2006
- MUT/06/20 - 10.1 Revised procedure for holding committee meetings in open session
- MUT/06/21 - Draft working paper on use of in-vivo rat liver UDS assay compared to rat liver COMET assay data
- MUT/06/22 - Risk factors affecting the formation of chromosomal aberration and micronuclei in peripheral blood lymphocytes. Draft working paper and additional data
2005
- MUT/05/1- Further information and follow-up of October 2004 review (Annex VI)
- MUT/05/3 - Mutagenicity of Halonitromethanes
- MUT/05/4 - Development of cII transgenic mutation assay. Comparison with lacI and lacZ systems
- MUT/05/6 - Submitted papers for February 2005 meeting MUT/05/6add1; MUT/05/6add2
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MUT/05/7 -Papers for information: - Brian Q et al, Occ Environ Med 61, 999-1005, 2004; Votano J R et al, Mutagenesis, vol 19, 365-377, 2004 & Yamazaki Y et al, Mutation Research, 562, 151-162, 2004.
- MUT/05/9 - Cumulative exposure
- MUT/05/10 - Post February 2005 meet;selection of studies for review
- MUT/05/11 - Epidemiology overview of selected studies MUT/05/11add
- MUT/05/14 - Mutagenicity data on PFOS and PFOA
- MUT/05/15 - Mutagenicity data on nanomaterials
- MUT/05/16 - Draft working paper on mutagenicity of Halonitromethanes
- MUT/05/17 - Draft working paper on cII transgenic mutation assay
- MUT/05/18 - COT/COC/COM overview of nanomaterial toxicology
2004
- MUT/04/2 - Application to mechanism of benzene induced leukaemia
- MUT/04/3 - Genotoxic carcinogens and DNA repair at low doses: Advice from COM
- MUT/04/4 - Significance of paper by Thilly on environmental Mutagens
- MUT/04/5 - Draft OECD guideline on in-vitro micronucleus test: Use of cell or culture as statistical unit?
- MUT/04/8 - 2,3-Dichloropropan-2-ol: consideration of new mutagenicity data
- MUT/04/9 - Holding Committee meetings in open session - experience of COT
- MUT/04/12 - Malachite green: consideration of new data
- MUT/04/13 - SCCNFP Recommendations on testing cosmetic ingredients for mutagenicity
- MUT/04/14 - Genotoxic carcinogens and DNA repair at low doses,annex 1
- MUT/04/19 - Biomonitoring studies from EU of genotoxicity in pesticides applicators , annex I , annex II , annex III , annex IV and annex V
- MUT/04/20 - Review of biomonitoring studies from Croatia
- MUT/04/21 - Reassessment of toxicological testing of tobacco products
- MUT/04/22 - Horizon scanning
2003
- MUT/03/8 - Horizon scanning
- MUT/03/9 - 2-Phenylphenol: update on mutagenicity
- MUT/03/12 - Mammalian Cell Mutation Assays
- MUT/03/13 - Strategy for Investigating Germ Cell Mutagens
- MUT/03/14 - Mutagenicity of Chromium Picolinate