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2009

2008

2007

2006

 

 

2005

2004

2003

2001

 

 

 

2008

  • MUT/08/1 - Review of Genotoxicity of Acrylamide: Review of additional data December 2007 and January 2008 from PPG
  • MUT/08/3 - Review of COM guidance: Discussion paper on scope and process
  • MUT/08/4 - Draft working paper on mutagenicity assessment of chemical mixtures
  • MUT/08/6 - Additional data on acrylamide
  • MUT/08/7 - Overview of genotoxicity of glycidamide
  • MUT/08/8 - Review of genotoxicity data on phenol
  • MUT/08/9 -  Generic papers on hypothermia and hyperthermia and induction of MN in                   rodent  
  • MUT/08/10 - Mutagenicity evaluation of impurities
  • MUT/08/11 - Scope of review of COM guidance
  • MUT/08/12 - Consideration of draft ICH guidance
  • MUT/08/13 - Aclonifen (closed session)
  • MUT/08/16 - Phenol: Consideration of Draft Working Paper
  • MUT/08/18 - Review of COM Guidance: Secretariat Meeting
  • MUT/08/19 - Provisional informatin in ILSI-HESI research on Toxicogenomic

                              approaches to genotoxicity

  • MUT/08/20 - Fourth Draft Statement on the Genotoxicity of Acrylamide

 

2007

  • MUT/07/01 - Formaldehyde: Evidence for systemic mutagenicity
  • MUT/07/02 - The Lowest Effective Dose (LED for in-vivo genotoxicity); a possible approach to mutagen potency ranking
  • MUT/07/03 - Initial discussion paper on mutagenicity of mixtures
  • MUT/07/04 - Benzimidazoles: an approach to defining a common aneugenic grouping
  • MUT/07/06 - Strategies for mutagenicity testing post 7th Amendment to the EU Cosmetics Directive. Discussion of commentary paper from Tweats DJ et al published Mutagenesis, 2 Dec 2006
  • MUT/07/8 - Use of the LED for potency ranking of in-vivo mutagens
  • MUT/07/9 - Mutagenicity of Terephthalic acid - Additional cytogenetics data
  • MUT/07/10 - Additional summary information on GADD45a-GFP assay
  • MUT/07/11 - Development of an OECD guideline for the in-vitro Micronucleus assay
  • MUT/07/12 - Draft working paper on Formaldehyde (written comments)
  • MUT/07/14 Presentation - The TK6 GADD45a-GFP Genotoxicity assay Dr R Walmsley (University of Manchester)
  • MUT/07/15 - Mutagenicity of mixtures. 2nd discussion paper. Evaluation of interactions using mutagenicity tests
  • MUT/07/17 and annex A - EU Risk Assessment Summary and Overview of the COM review strategy
  • MUT/07/20 - Aneuploidy: Action both oncogenically and as a tumour suppressor
  • MUT/07/22 - Revised code of practice for observers
  • MUT/07/23 - Sodium Benzoate and Potassium Sorbater
  • MUT/07/24 - Draft statement on Terephthalic Acid

2006

  • MUT/06/1 ; Annex 1 ; Annex 2 -- Background Background variation in Micronuclei in peripheral blood lymphocytes; Discussion paper on risk factors
  • MUT/06/2 - Biological Effects of Wear Debris Generated from Metal on Metal Bearing Surfaces: Evidence for Genotoxicity
  • MUT/06/3 - A comparison of the sensitivities of the in vivo rat liver UDS assay with the in vivo COMET assay
  • MUT/06/8 - Benzimidazoles: Discussion of a common mechanism group (Annex 1 in confidence)
  • MUT/06/9 - Terephthalic acid: Update on mutagenicity data (Annexes A - E in confidence)
  • MUT/06/10 - Comparative risk assessment: Initial discussions
  • MUT/06/11 - Discussion of risk factors for background variance of cytogenticity in Peripheral Blood Lymphocytes
  • MUT/06/15 - Role of methylation status: Transgenerational effects of methylation
  • MUT/06/16 - Comparative risk assessment update of COC discussion
  • MUT/06/17 - Do dose response thresholds exist for genotoxic alkylating agents? GJS Jenkins et al Mutagenesis, 20, (6), 389-398, 2005. Evidence for practical thresholds for clastogenic agents.
  • MUT/06/20 - 10.1 Revised procedure for holding committee meetings in open session
  • MUT/06/21 - Draft working paper on use of in-vivo rat liver UDS assay compared to rat liver COMET assay data
  • MUT/06/22 - Risk factors affecting the formation of chromosomal aberration and micronuclei in peripheral blood lymphocytes. Draft working paper and additional data

2005

  • MUT/05/3 - Mutagenicity of Halonitromethanes
  • MUT/05/4 - Development of cII transgenic mutation assay. Comparison with lacI and lacZ systems
  • MUT/05/7 -Papers for information: - Brian Q et al, Occ Environ Med 61, 999-1005, 2004; Votano J R et al, Mutagenesis, vol 19, 365-377, 2004 & Yamazaki Y et al, Mutation Research, 562, 151-162, 2004.

  • MUT/05/10 - Post February 2005 meet;selection of studies for review
  • MUT/05/12 ; Table - Discussion paper on evaluation of positive studies & control data
  • MUT/05/14 - Mutagenicity data on PFOS and PFOA
  • MUT/05/15 - Mutagenicity data on nanomaterials
  • MUT/05/16 - Draft working paper on mutagenicity of Halonitromethanes
  • MUT/05/17 - Draft working paper on cII transgenic mutation assay
  • MUT/05/18 - COT/COC/COM overview of nanomaterial toxicology


2004

  • MUT/04/1 - Update on joint COT/COC/COM meeting October 2001
  • MUT/04/2 - Application to mechanism of benzene induced leukaemia
  • MUT/04/3 - Genotoxic carcinogens and DNA repair at low doses: Advice from COM
  • MUT/04/4 - Significance of paper by Thilly on environmental Mutagens
  • MUT/04/5 - Draft OECD guideline on in-vitro micronucleus test: Use of cell or culture as statistical unit?
  • MUT/04/8 - 2,3-Dichloropropan-2-ol: consideration of new mutagenicity data
  • MUT/04/9 - Holding Committee meetings in open session - experience of COT
  • MUT/04/13 - SCCNFP Recommendations on testing cosmetic ingredients for mutagenicity
  • MUT/04/21 - Reassessment of toxicological testing of tobacco products

2003


2001